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Small molecule allosteric modulation of the adenosine A(1) receptor

G protein-coupled receptors (GPCRs) represent the target for approximately a third of FDA-approved small molecule drugs. The adenosine A(1) receptor (A(1)R), one of four adenosine GPCR subtypes, has important (patho)physiological roles in humans. A(1)R has well-established roles in the regulation of...

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Detalles Bibliográficos
Autores principales: Nguyen, Anh T. N., Tran, Quan L., Baltos, Jo-Anne, McNeill, Samantha M., Nguyen, Diep T. N., May, Lauren T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331460/
https://www.ncbi.nlm.nih.gov/pubmed/37435481
http://dx.doi.org/10.3389/fendo.2023.1184360

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