Bromodomain-containing Protein 4 regulates innate inflammation via modulation of alternative splicing

INTRODUCTION: Bromodomain-containing Protein 4 (BRD4) is a transcriptional regulator which coordinates gene expression programs controlling cancer biology, inflammation, and fibrosis. In the context of airway viral infection, BRD4-specific inhibitors (BRD4i) block the release of pro-inflammatory cyt...

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Detalles Bibliográficos
Autores principales: Mann, Morgan W., Fu, Yao, Gearhart, Robert L., Xu, Xiaofang, Roberts, David S., Li, Yi, Zhou, Jia, Ge, Ying, Brasier, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331468/
https://www.ncbi.nlm.nih.gov/pubmed/37435059
http://dx.doi.org/10.3389/fimmu.2023.1212770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331468/
https://www.ncbi.nlm.nih.gov/pubmed/37435059
http://dx.doi.org/10.3389/fimmu.2023.1212770

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