Engineering of increased L-Threonine production in bacteria by combinatorial cloning and machine learning

The goal of this study is to develop a general strategy for bacterial engineering using an integrated synthetic biology and machine learning (ML) approach. This strategy was developed in the context of increasing L-threonine production in Escherichia coli ATCC 21277. A set of 16 genes was initially...

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Detalles Bibliográficos
Autores principales: Hanke, Paul, Parrello, Bruce, Vasieva, Olga, Akins, Chase, Chlenski, Philippe, Babnigg, Gyorgy, Henry, Chris, Foflonker, Fatima, Brettin, Thomas, Antonopoulos, Dionysios, Stevens, Rick, Fonstein, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331477/
https://www.ncbi.nlm.nih.gov/pubmed/37435441
http://dx.doi.org/10.1016/j.mec.2023.e00225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331477/
https://www.ncbi.nlm.nih.gov/pubmed/37435441
http://dx.doi.org/10.1016/j.mec.2023.e00225

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