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Design and analysis of factorial clinical trials: The impact of one treatment's effectiveness on the statistical power and required sample size of the other

Factorial allow for the simultaneous evaluation of more than one treatment, by randomizing patients to their possible combinations, including control. However, the statistical power of one treatment can be influenced by the effectiveness of the other, a matter that has not been widely recognized. In...

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Detalles Bibliográficos
Autores principales: Walter, Stephen D., Belo, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331518/
https://www.ncbi.nlm.nih.gov/pubmed/37077125
http://dx.doi.org/10.1177/09622802231163332