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AAV induces hepatic necroptosis and carcinoma in diabetic and obese mice dependent on Pebp1 pathway

Obesity and diabetes are risk factors for hepatocellular carcinoma (HCC); however, the underlying mechanisms are yet to be elucidated. Adeno‐associated virus (AAV) frequently infects humans and has been widely used in gene therapy, but the risk of AAV infection such as HCC should be further evaluate...

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Detalles Bibliográficos
Autores principales: Cheng, Yalan, Zhang, Zhentong, Gao, Peidong, Lai, Hejin, Zhong, Wuling, Feng, Ning, Yang, Yale, Yu, Huimin, Zhang, Yali, Han, Yumo, Dong, Jieya, He, Zhishui, Huang, Rui, Zhai, Qiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331584/
https://www.ncbi.nlm.nih.gov/pubmed/37272212
http://dx.doi.org/10.15252/emmm.202217230