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A multilevel screening pipeline in zebrafish identifies therapeutic drugs for GAN

Giant axonal neuropathy (GAN) is a fatal neurodegenerative disorder for which there is currently no treatment. Affecting the nervous system, GAN starts in infancy with motor deficits that rapidly evolve toward total loss of ambulation. Using the gan zebrafish model that reproduces the loss of motili...

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Detalles Bibliográficos
Autores principales: Lescouzères, Léa, Hassen‐Khodja, Cédric, Baudot, Anaïs, Bordignon, Benoît, Bomont, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331585/
https://www.ncbi.nlm.nih.gov/pubmed/37144692
http://dx.doi.org/10.15252/emmm.202216267