Neurofibromatosis-1 Gene Mutational Profiles Differ Between Syndromic Disease and Sporadic Cancers

OBJECTIVES: Variants in the neurofibromatosis type 1 (NF1) gene are not only responsible for the NF1 cancer predisposition syndrome, but also frequently identified in cancers arising in the general population. While germline variants are pathogenic, it is not known whether those that arise in cancer...

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Detalles Bibliográficos
Autores principales: Bewley, Alice F., Akinwe, Titilope M., Turner, Tychele N., Gutmann, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Clinical/Scientific Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331586/
https://www.ncbi.nlm.nih.gov/pubmed/37435433
http://dx.doi.org/10.1212/NXG.0000000000200003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331586/
https://www.ncbi.nlm.nih.gov/pubmed/37435433
http://dx.doi.org/10.1212/NXG.0000000000200003

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