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FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice

FAM3C/ILEI is an important cytokine for tumor progression and metastasis. However, its involvement in inflammation remains elusive. Here, we show that ILEI protein is highly expressed in psoriatic lesions. Inducible keratinocyte‐specific ILEI overexpression in mice (K5‐ILEI ( ind )) recapitulates ma...

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Detalles Bibliográficos
Autores principales: Malik, Barizah, Vokic, Iva, Mohr, Thomas, Poppelaars, Marle, Holcmann, Martin, Novoszel, Philipp, Timelthaler, Gerald, Lendl, Thomas, Krauss, Dana, Elling, Ulrich, Mildner, Michael, Penninger, Josef M, Petzelbauer, Peter, Sibilia, Maria, Csiszar, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331587/
https://www.ncbi.nlm.nih.gov/pubmed/37226685
http://dx.doi.org/10.15252/emmm.202216758