A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease

The Keap1-Nrf2 pathway has been established as a therapeutic target for Alzheimer's disease (AD). Directly inhibiting the protein-protein interaction (PPI) between Keap1 and Nrf2 has been reported as an effective strategy for treating AD. Our group has validated this in an AD mouse model for th...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Xu, Lijuan, Zheng, Dongpeng, Wang, Jue, Liu, Guodong, Mo, Zixin, Liu, Chao, Zhang, Wannian, Yu, Jianqiang, Xing, Chengguo, He, Ling, Zhuang, Chunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331597/
https://www.ncbi.nlm.nih.gov/pubmed/37385075
http://dx.doi.org/10.1016/j.redox.2023.102793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331597/
https://www.ncbi.nlm.nih.gov/pubmed/37385075
http://dx.doi.org/10.1016/j.redox.2023.102793

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