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Atypical pattern of response in rectal cancer after neoadjuvant pembrolizumab treatment: a case report, literature review, and proposed management model

BACKGROUND: Immunotherapy is the first-line treatment in patients with advanced microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) colorectal cancer (CRC). Although immune checkpoint inhibitors (ICIs) for locally advanced rectal cancer (LARC) are not yet a standard, the resu...

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Detalles Bibliográficos
Autores principales: Tissera, Natalia S., Esteso, Federico, Luca, Romina, Enrico, Diego, Waisberg, Federico, Rodriguez, Andrés, Bruno, Luisina, Kucharczyk, Mariana, Amat, Mora, García, Ximena, Pombo, Teresa, Salazar, Ivana Pedraza, Loria, Fernando Sanchez, Huertas, Eduardo, Galli, Mariana, Chacón, Matías, O’Connor, Juan Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331748/
https://www.ncbi.nlm.nih.gov/pubmed/37435212
http://dx.doi.org/10.21037/jgo-22-1140