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Anti-NGF treatment worsens subchondral bone and cartilage measures while improving symptoms in floor-housed rabbits with osteoarthritis

Objective: Osteoarthritis (OA) is a common joint disorder often affecting the knee. It is characterized by alterations of various joint tissues including subchondral bone and by chronic pain. Anti-nerve growth factor (NGF) antibodies have demonstrated improvement in pain associated with OA in phase...

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Detalles Bibliográficos
Autores principales: Menges, Stephanie, Michaelis, Martin, Kleinschmidt-Dörr, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331818/
https://www.ncbi.nlm.nih.gov/pubmed/37435308
http://dx.doi.org/10.3389/fphys.2023.1201328