Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane

A general microwave synthesis of 4-oxo-3,4-dihydroquinazolin-2-yl propanoic acids and their diamide precursors from the corresponding substituted benzamide and succinic anhydride is described, using pinane as a sustainable solvent that favors the cyclization step. The conditions are some of the most...

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Detalles Bibliográficos
Autores principales: Richieu, Antoine, Bertrand, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331922/
https://www.ncbi.nlm.nih.gov/pubmed/37435375
http://dx.doi.org/10.1039/d3ra03702a
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author Richieu, Antoine
Bertrand, Philippe
author_facet Richieu, Antoine
Bertrand, Philippe
author_sort Richieu, Antoine
collection PubMed
description A general microwave synthesis of 4-oxo-3,4-dihydroquinazolin-2-yl propanoic acids and their diamide precursors from the corresponding substituted benzamide and succinic anhydride is described, using pinane as a sustainable solvent that favors the cyclization step. The conditions are some of the most simple and cost effective reported.
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spelling pubmed-103319222023-07-11 Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane Richieu, Antoine Bertrand, Philippe RSC Adv Chemistry A general microwave synthesis of 4-oxo-3,4-dihydroquinazolin-2-yl propanoic acids and their diamide precursors from the corresponding substituted benzamide and succinic anhydride is described, using pinane as a sustainable solvent that favors the cyclization step. The conditions are some of the most simple and cost effective reported. The Royal Society of Chemistry 2023-07-10 /pmc/articles/PMC10331922/ /pubmed/37435375 http://dx.doi.org/10.1039/d3ra03702a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Richieu, Antoine
Bertrand, Philippe
Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
title Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
title_full Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
title_fullStr Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
title_full_unstemmed Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
title_short Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
title_sort convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331922/
https://www.ncbi.nlm.nih.gov/pubmed/37435375
http://dx.doi.org/10.1039/d3ra03702a
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