Single-cell multi-gene identification of somatic mutations and gene rearrangements in cancer

In this proof-of-concept study, we developed a single-cell method that provides genotypes of somatic alterations found in coding regions of messenger RNAs and integrates these transcript-based variants with their matching cell transcriptomes. We used nanopore adaptive sampling on single-cell complem...

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Detalles Bibliográficos
Autores principales: Grimes, Susan M, Kim, Heon Seok, Roy, Sharmili, Sathe, Anuja, Ayala, Carlos I, Bai, Xiangqi, Almeda-Notestine, Alison F, Haebe, Sarah, Shree, Tanaya, Levy, Ronald, Lau, Billy T, Ji, Hanlee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Cancer Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331933/
https://www.ncbi.nlm.nih.gov/pubmed/37435532
http://dx.doi.org/10.1093/narcan/zcad034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331933/
https://www.ncbi.nlm.nih.gov/pubmed/37435532
http://dx.doi.org/10.1093/narcan/zcad034

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