A novel interface between the N-terminal and coiled-coil domain of STAT1 functions in an auto-inhibitory manner

BACKGROUND: STAT1 is an intracellular signaling molecule that is crucially involved in the regulation of the innate immune system by activation of defense mechanisms against microbial pathogens. Phosphorylation-dependent activation of the STAT1 transcription factor is associated with a conversion fr...

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Detalles Bibliográficos
Autores principales: Remling, Linus, Gregus, Anke, Wirths, Oliver, Meyer, Thomas, Staab, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331961/
https://www.ncbi.nlm.nih.gov/pubmed/37430250
http://dx.doi.org/10.1186/s12964-023-01124-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331961/
https://www.ncbi.nlm.nih.gov/pubmed/37430250
http://dx.doi.org/10.1186/s12964-023-01124-1

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