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A novel interface between the N-terminal and coiled-coil domain of STAT1 functions in an auto-inhibitory manner

BACKGROUND: STAT1 is an intracellular signaling molecule that is crucially involved in the regulation of the innate immune system by activation of defense mechanisms against microbial pathogens. Phosphorylation-dependent activation of the STAT1 transcription factor is associated with a conversion fr...

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Detalles Bibliográficos
Autores principales:	Remling, Linus, Gregus, Anke, Wirths, Oliver, Meyer, Thomas, Staab, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331961/ https://www.ncbi.nlm.nih.gov/pubmed/37430250 http://dx.doi.org/10.1186/s12964-023-01124-1

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