Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial

INTRODUCTION/AIMS: Muscle cramps are a common and often disabling symptom in amyotrophic lateral sclerosis (ALS), a devastating and incurable neurodegenerative disorder. To date, there are no medications specifically approved for the treatment of muscle cramps. Ameliorating muscle cramps in ALS may...

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Detalles Bibliográficos
Autores principales: Mitsumoto, Hiroshi, Cheung, Ken, Oskarsson, Björn, Andrews, Howard F., Jang, Grace E., Andrews, Jinsy A., Shah, Jaimin S., Fernandes, Joseph Americo, McElhiney, Martin, Santella, Regina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332004/
https://www.ncbi.nlm.nih.gov/pubmed/37430314
http://dx.doi.org/10.1186/s13063-023-07424-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332004/
https://www.ncbi.nlm.nih.gov/pubmed/37430314
http://dx.doi.org/10.1186/s13063-023-07424-8

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