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γ-2 and GSG1L bind with comparable affinities to the tetrameric GluA1 core

BACKGROUND: The AMPA-type ionotropic glutamate receptor mediates fast excitatory neurotransmission in the brain. A variety of auxiliary subunits regulate its gating properties, assembly, and trafficking, but it is unknown if the binding of these auxiliary subunits to the receptor core is dynamically...

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Detalles Bibliográficos
Autores principales: Yu, Chenlu, Runge, Hendrik F. P., Mukhopadhyay, Antara, Zolles, Gerd, Ulbrich, Maximilian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332039/
https://www.ncbi.nlm.nih.gov/pubmed/37430208
http://dx.doi.org/10.1186/s11658-023-00470-9