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The role of TET2-mediated ROBO4 hypomethylation in the development of diabetic retinopathy
BACKGROUND: In diabetic retinopathy, increasing evidence points to a link between the pathogenesis of retinal microangiopathy and the endothelial cell-specific factor roundabout4 (ROBO4). According to earlier research, specificity protein 1 (SP1) enhances the binding to the ROBO4 promoter, increasin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332081/ https://www.ncbi.nlm.nih.gov/pubmed/37430272 http://dx.doi.org/10.1186/s12967-023-04310-4 |