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TERC haploid cell reprogramming: a novel therapeutic strategy for aplastic anemia

The telomerase RNA component (TERC) gene plays an important role in telomerase-dependent extension and maintenance of the telomeres. In the event of TERC haploinsufficiency, telomere length is often affected; this, in turn, can result in the development of progeria-related diseases such as aplastic...

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Detalles Bibliográficos
Autores principales: Tang, Xinyu, Xu, Ruirong, Wang, Yan, Chen, Kaiqing, Cui, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332096/
https://www.ncbi.nlm.nih.gov/pubmed/37424004
http://dx.doi.org/10.1186/s10020-023-00691-w