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SARS-CoV-2 Nsp1 mediated mRNA degradation requires mRNA interaction with the ribosome
Nsp1 is a SARS-CoV-2 host shutoff factor that both represses cellular translation and promotes host RNA decay. However, it is unclear how these two activities are connected and interact with normal translation processes. Here, we performed mutational analyses of Nsp1, and these revealed that both th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332192/ https://www.ncbi.nlm.nih.gov/pubmed/37415298 http://dx.doi.org/10.1080/15476286.2023.2231280 |