Cytotoxic necrotizing factor 1 hinders colon tumorigenesis induced by colibactin-producing Escherichia coli in Apc(Min/+) mice

Colorectal cancer (CRC) patients are frequently colonized by colibactin-producing Escherichia coli (CoPEC) (>40%), which enhances tumorigenesis in mouse models of CRC. We observed that 50% of CoPEC also contains the cnf1 gene, which encodes cytotoxic necrotizing factor-1 (CNF1), an enhancer of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Chat, Héloïse, Dalmasso, Guillaume, Godfraind, Catherine, Bonnin, Virginie, Beyrouthy, Racha, Bonnet, Mathilde, Barnich, Nicolas, Mettouchi, Amel, Lemichez, Emmanuel, Bonnet, Richard, Delmas, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332217/
https://www.ncbi.nlm.nih.gov/pubmed/37417545
http://dx.doi.org/10.1080/19490976.2023.2229569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332217/
https://www.ncbi.nlm.nih.gov/pubmed/37417545
http://dx.doi.org/10.1080/19490976.2023.2229569

Ejemplares similares