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Mutation of brain aromatase disrupts spawning behavior and reproductive health in female zebrafish

Aromatase (Cyp19a1) is the steroidogenic enzyme that converts androgens into bioactive estrogens, and hence is in a pivotal position to mediate reproduction and sexual behavior. In teleosts, there are two aromatase paralogs: cyp19a1a that is highly expressed in granulosa and Leydig cells in the gona...

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Detalles Bibliográficos
Autores principales: Shaw, Katherine, Therrien, Mylène, Lu, Chunyu, Liu, Xiaochun, Trudeau, Vance L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332311/
https://www.ncbi.nlm.nih.gov/pubmed/37435485
http://dx.doi.org/10.3389/fendo.2023.1225199