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N-terminal lid swapping contributes to the substrate specificity and activity of thermophilic lipase TrLipE

TrLipE is a thermophilic lipase that has potential commercial applications because of its catalytic ability under extreme conditions. Consistent with most lipases, the lid of TrLipE is located over the catalytic pocket, controls the substrate channel to the active center, and regulates the substrate...

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Detalles Bibliográficos
Autores principales: Fang, Yakun, Liu, Fan, Shi, Yi, Yang, Ting, Xin, Yu, Gu, Zhenghua, Shi, Guiyang, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332459/
https://www.ncbi.nlm.nih.gov/pubmed/37434709
http://dx.doi.org/10.3389/fmicb.2023.1193955