Fluorescence microscopy-based sensitive method to quantify dopaminergic neurodegeneration in a Drosophila model of Parkinson’s disease

Death of dopaminergic (DAergic) neurons in the substantia nigra pars compacta of the human brain is the characteristic pathological feature of Parkinson’s disease (PD). On exposure to neurotoxicants, Drosophila too exhibits mobility defects and diminished levels of brain dopamine. In the fly model o...

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Detalles Bibliográficos
Autores principales: Ayajuddin, Mohamad, Chaurasia, Rahul, Das, Abhik, Modi, Priyanka, Phom, Limamanen, Koza, Zevelou, Yenisetti, Sarat Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332464/
https://www.ncbi.nlm.nih.gov/pubmed/37434762
http://dx.doi.org/10.3389/fnins.2023.1158858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332464/
https://www.ncbi.nlm.nih.gov/pubmed/37434762
http://dx.doi.org/10.3389/fnins.2023.1158858

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