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Absolute quantification of neuromelanin in formalin-fixed human brains using absorbance spectrophotometry

Parkinson’s disease is characterised by a visual, preferential degeneration of the pigmented neurons in the substantia nigra. These neurons are pigmented by neuromelanin which decreases in Parkinson’s disease. Not much is known about NM as it is difficult to study and quantify, primarily due to its...

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Detalles Bibliográficos
Autores principales: Chand, Dipshay Avi, Scadeng, Miriam, Dieriks, Birger Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332574/
https://www.ncbi.nlm.nih.gov/pubmed/37428719
http://dx.doi.org/10.1371/journal.pone.0288327