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Identification of a novel lipoic acid biosynthesis pathway reveals the complex evolution of lipoate assembly in prokaryotes

Lipoic acid is an essential biomolecule found in all domains of life and is involved in central carbon metabolism and dissimilatory sulfur oxidation. The machineries for lipoate assembly in mitochondria and chloroplasts of higher eukaryotes, as well as in the apicoplasts of some protozoa, are all of...

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Detalles Bibliográficos
Autores principales: Tanabe, Tomohisa Sebastian, Grosser, Martina, Hahn, Lea, Kümpel, Carolin, Hartenfels, Hanna, Vtulkin, Evelyn, Flegler, Wanda, Dahl, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332631/
https://www.ncbi.nlm.nih.gov/pubmed/37368881
http://dx.doi.org/10.1371/journal.pbio.3002177