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Case Report: Longitudinal monitoring of clonal evolution by circulating tumor DNA for resistance to anti-EGFR antibody in a case of metastatic colorectal cancer

BACKGROUND: Treatment with anti-EGFR antibody has been shown to prolong survival in patients with RAS wild-type metastatic colorectal cancer (mCRC). However, even patients who initially respond to anti-EGFR antibody therapy, almost without exception, develop resistance to the therapy and then fail t...

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Detalles Bibliográficos
Autores principales: Sagawa, Tamotsu, Sato, Yasushi, Hirakawa, Masahiro, Hamaguchi, Kyoko, Tamura, Fumito, Nagashima, Hiroyuki, Fujikawa, Koshi, Okamoto, Koichi, Kawano, Yutaka, Sogabe, Masahiro, Miyamoto, Hiroshi, Takayama, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332633/
https://www.ncbi.nlm.nih.gov/pubmed/37434969
http://dx.doi.org/10.3389/fonc.2023.1203296