MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia

Hypoxia requires metabolic adaptations to sustain energetically demanding cellular activities. While the metabolic consequences of hypoxia have been studied extensively in cancer cell models, comparatively little is known about how primary cell metabolism responds to hypoxia. Thus, we developed meta...

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Detalles Bibliográficos
Autores principales: Copeland, Courtney A, Olenchock, Benjamin A, Ziehr, David, McGarrity, Sarah, Leahy, Kevin, Young, Jamey D, Loscalzo, Joseph, Oldham, William M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332812/
https://www.ncbi.nlm.nih.gov/pubmed/37428010
http://dx.doi.org/10.7554/eLife.82597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332812/
https://www.ncbi.nlm.nih.gov/pubmed/37428010
http://dx.doi.org/10.7554/eLife.82597

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