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A novel peptide ‘T14’ reflects age and photo-aging in human skin

T14 is a 14mer peptide derived from the C-terminus of acetylcholinesterase (AChE). Once cleaved, it is independently bioactive of the parent molecule and enhances calcium influx in different cell types, in a range of scenarios: it binds to an allosteric site selectively on the alpha-7 receptor, wher...

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Detalles Bibliográficos
Autores principales: Rocha, Sheila, Ratés, Sara Garcia, Moswete, Tumisang, Kalleberg, Kristopher, Villa, Anna, Harcup, Jason P., Greenfield, Susan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333063/
https://www.ncbi.nlm.nih.gov/pubmed/37382595
http://dx.doi.org/10.18632/aging.204844