Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression

The development of transgenic mouse models that express genes of interest in specific cell types has transformed our understanding of basic biology and disease. However, generating these models is time- and resource-intensive. Here we describe a model system, SELective Expression and Controlled Tran...

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Detalles Bibliográficos
Autores principales: Zengel, James, Wang, Yu Xin, Seo, Jai Woong, Ning, Ke, Hamilton, James N., Wu, Bo, Raie, Marina, Holbrook, Colin, Su, Shiqi, Clements, Derek R., Pillay, Sirika, Puschnik, Andreas S., Winslow, Monte M., Idoyaga, Juliana, Nagamine, Claude M., Sun, Yang, Mahajan, Vinit B., Ferrara, Katherine W., Blau, Helen M., Carette, Jan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333121/
https://www.ncbi.nlm.nih.gov/pubmed/37291262
http://dx.doi.org/10.1038/s41592-023-01896-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333121/
https://www.ncbi.nlm.nih.gov/pubmed/37291262
http://dx.doi.org/10.1038/s41592-023-01896-x

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