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Learning consistent subcellular landmarks to quantify changes in multiplexed protein maps

Highly multiplexed imaging holds enormous promise for understanding how spatial context shapes the activity of the genome and its products at multiple length scales. Here, we introduce a deep learning framework called CAMPA (Conditional Autoencoder for Multiplexed Pixel Analysis), which uses a condi...

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Detalles Bibliográficos
Autores principales: Spitzer, Hannah, Berry, Scott, Donoghoe, Mark, Pelkmans, Lucas, Theis, Fabian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333128/
https://www.ncbi.nlm.nih.gov/pubmed/37248388
http://dx.doi.org/10.1038/s41592-023-01894-z