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Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation

Cannabinoid receptor 2 (CB2) signaling modulates microglial responses to inflammatory stimuli. Our previous studies demonstrated that genetic deletion of CB2 inhibits microglial activation during inflammatory stimulation of toll-like receptors (TLRs) or in neurodegenerative conditions. However, we c...

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Detalles Bibliográficos
Autores principales: Olabiyi, Bolanle Fatimat, Schmoele, Anne-Caroline, Beins, Eva Carolina, Zimmer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333177/
https://www.ncbi.nlm.nih.gov/pubmed/37429837
http://dx.doi.org/10.1038/s41598-023-37702-z