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Beyond DNA sensing: expanding the role of cGAS/STING in immunity and diseases
Cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS) is a DNA sensor that elicits a robust type I interferon response by recognizing ubiquitous danger-associated molecules. The cGAS/stimulator of interferon genes (cGAS/STING) is activated by endogenous DNA, including DNA re...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pharmaceutical Society of Korea
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333371/ https://www.ncbi.nlm.nih.gov/pubmed/37354378 http://dx.doi.org/10.1007/s12272-023-01452-3 |