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Acute and Chronic Macrophage Differentiation Modulates TREM2 in a Personalized Alzheimer’s Patient-Derived Assay

Neuroinflammation plays a pivotal role in the pathogenesis of Alzheimer`s disease (AD). Brain macrophage populations differentially modulate the immune response to AD pathology according to the disease stage. Triggering receptor expressed on myeloid cells 2 (TREM2) is known to play a protective role...

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Detalles Bibliográficos
Autores principales: Cosma, Nicoleta-Carmen, Eren, Neriman, Üsekes, Berk, Gerike, Susanna, Heuser, Isabella, Peters, Oliver, Hellmann-Regen, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333375/
https://www.ncbi.nlm.nih.gov/pubmed/37198381
http://dx.doi.org/10.1007/s10571-023-01351-7