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Acute and Chronic Macrophage Differentiation Modulates TREM2 in a Personalized Alzheimer’s Patient-Derived Assay
Neuroinflammation plays a pivotal role in the pathogenesis of Alzheimer`s disease (AD). Brain macrophage populations differentially modulate the immune response to AD pathology according to the disease stage. Triggering receptor expressed on myeloid cells 2 (TREM2) is known to play a protective role...
Autores principales: | Cosma, Nicoleta-Carmen, Eren, Neriman, Üsekes, Berk, Gerike, Susanna, Heuser, Isabella, Peters, Oliver, Hellmann-Regen, Julian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333375/ https://www.ncbi.nlm.nih.gov/pubmed/37198381 http://dx.doi.org/10.1007/s10571-023-01351-7 |
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