Effect of P53 nuclear localization mediated by G3BP1 on ferroptosis in acute liver failure

This study investigated whether G3BP1 could regulate ferroptosis in hepatocytes during ALF by affecting the entry of P53 into the nucleus. Promoting G3BP1 expression could inhibit P53 entry by binding to the nuclear localization sequence of P53. The inhibition of SLC7A11 transcription was weakened a...

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Detalles Bibliográficos
Autores principales: Li, Wenyuan, Li, Wei, Li, Xun, Wang, Luwen, Wang, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333398/
https://www.ncbi.nlm.nih.gov/pubmed/37243773
http://dx.doi.org/10.1007/s10495-023-01856-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333398/
https://www.ncbi.nlm.nih.gov/pubmed/37243773
http://dx.doi.org/10.1007/s10495-023-01856-y

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