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IGF2BP2 promotes lncRNA DANCR stability mediated glycolysis and affects the progression of FLT3-ITD + acute myeloid leukemia

Internal tandem duplication (ITD) is the most common type of FLT3 mutation (FLT3-ITD), accounting for about 25% of AML patients. The expression of DANCR in FLT3-ITD AML had not been paid attention to, and whether its regulatory relationship with IGF2BP2 can affect the progression of FLT3-ITD AML was...

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Detalles Bibliográficos
Autores principales: Wu, Shenghao, Chi, Changwei, Weng, Shanshan, Zhou, Wenjin, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333402/
https://www.ncbi.nlm.nih.gov/pubmed/37060505
http://dx.doi.org/10.1007/s10495-023-01846-0