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IL-27 promotes cardiac fibroblast activation and aggravates cardiac remodeling post myocardial infarction

Excessive and chronic inflammation post myocardial infarction (MI) causes cardiac fibrosis and progressive ventricular remodeling, which leads to heart failure. We previously found high levels of IL-27 in the heart and serum until day 14 in murine cardiac ischemia‒reperfusion injury models. However,...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoxue, Meng, Qingshu, Gong, Shiyu, Shi, Shanshan, Liang, Xiaoting, Lin, Fang, Gong, Li, Liu, Xuan, Li, Yinzhen, Li, Mimi, Wei, Lu, Han, Wei, Gao, Leng, Liu, Zhongmin, Zhou, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333439/
https://www.ncbi.nlm.nih.gov/pubmed/37441391
http://dx.doi.org/10.1016/j.heliyon.2023.e17099