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IL-27 promotes cardiac fibroblast activation and aggravates cardiac remodeling post myocardial infarction
Excessive and chronic inflammation post myocardial infarction (MI) causes cardiac fibrosis and progressive ventricular remodeling, which leads to heart failure. We previously found high levels of IL-27 in the heart and serum until day 14 in murine cardiac ischemia‒reperfusion injury models. However,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333439/ https://www.ncbi.nlm.nih.gov/pubmed/37441391 http://dx.doi.org/10.1016/j.heliyon.2023.e17099 |