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DNA methylation-based classifier differentiates intrahepatic pancreato-biliary tumours

BACKGROUND: Differentiating intrahepatic cholangiocarcinomas (iCCA) from hepatic metastases of pancreatic ductal adenocarcinoma (PAAD) is challenging. Both tumours have similar morphological and immunohistochemical pattern and share multiple driver mutations. We hypothesised that DNA methylation-bas...

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Detalles Bibliográficos
Autores principales: Dragomir, Mihnea P., Calina, Teodor G., Perez, Eilís, Schallenberg, Simon, Chen, Meng, Albrecht, Thomas, Koch, Ines, Wolkenstein, Peggy, Goeppert, Benjamin, Roessler, Stephanie, Calin, George A., Sers, Christine, Horst, David, Roßner, Florian, Capper, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333440/
https://www.ncbi.nlm.nih.gov/pubmed/37348162
http://dx.doi.org/10.1016/j.ebiom.2023.104657