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CircSFMBT2-OA alleviates chondrocyte apoptosis and extracellular matrix degradation through repressing NF-κB/NLRP3 inflammasome activation

BACKGROUND: Intra-articular inflammation and cartilage degradation are the major pathological characteristics of osteoarthritis (OA). Mounting studies have revealed that circular RNAs (circRNAs) act as an important regulatory role in inflammatory diseases and are frequently dys-expressed in OA carti...

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Detalles Bibliográficos
Autores principales: He, Axiang, Liu, Yaru, Zhang, Renbo, Mao, Yanjie, Liu, Wanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333456/
https://www.ncbi.nlm.nih.gov/pubmed/37441407
http://dx.doi.org/10.1016/j.heliyon.2023.e17312