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Variability of the innate immune response is globally constrained by transcriptional bursting
Transcription of almost all mammalian genes occurs in stochastic bursts, however the fundamental control mechanisms that allow appropriate single-cell responses remain unresolved. Here we utilise single cell genomics data and stochastic models of transcription to perform global analysis of the toll-...
Autores principales: | Alachkar, Nissrin, Norton, Dale, Wolkensdorfer, Zsofia, Muldoon, Mark, Paszek, Pawel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333517/ https://www.ncbi.nlm.nih.gov/pubmed/37441161 http://dx.doi.org/10.3389/fmolb.2023.1176107 |
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