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One-carbon metabolism is required for epigenetic stability in the mouse placenta
One-carbon metabolism, including the folate cycle, has a crucial role in fetal development though its molecular function is complex and unclear. The hypomorphic Mtrr ( gt ) allele is known to disrupt one-carbon metabolism, and thus methyl group availability, leading to several developmental phenotyp...
Autores principales: | Senner, Claire E., Dong, Ziqi, Prater, Malwina, Branco, Miguel R., Watson, Erica D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333575/ https://www.ncbi.nlm.nih.gov/pubmed/37440923 http://dx.doi.org/10.3389/fcell.2023.1209928 |
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