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Unveiling the complexity of transcription factor networks in hematopoietic stem cells: implications for cell therapy and hematological malignancies

The functionality and longevity of hematopoietic tissue is ensured by a tightly controlled balance between self-renewal, quiescence, and differentiation of hematopoietic stem cells (HSCs) into the many different blood lineages. Cell fate determination in HSCs is influenced by signals from extrinsic...

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Detalles Bibliográficos
Autores principales: Benyoucef, Aissa, Haigh, Jody J., Brand, Marjorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333584/
https://www.ncbi.nlm.nih.gov/pubmed/37441426
http://dx.doi.org/10.3389/fonc.2023.1151343