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Chondroitin sulfate functionalized palmitic acid and cysteine cografted-quaternized chitosan for CD44 and gut microbiota dual-targeted delivery of curcumin

Curcumin (CUR) has a regulatory effect on the gut microbiota (GM), and its significant anti-inflammatory properties make it a research hotspot for inflammatory bowel disease (IBD) treatment. However, the low bioavailability and poor pharmacokinetic properties of CUR limit its practical application....

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Detalles Bibliográficos
Autores principales: Xie, Yinzhuo, Xu, Wei, Jin, Zheng, Zhao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333679/
https://www.ncbi.nlm.nih.gov/pubmed/37441137
http://dx.doi.org/10.1016/j.mtbio.2023.100617