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Inflammatory and tolerogenic myeloid cells determine outcome following human allergen challenge

Innate mononuclear phagocytic system (MPS) cells preserve mucosal immune homeostasis. We investigated their role at nasal mucosa following allergen challenge with house dust mite. We combined single-cell proteome and transcriptome profiling on nasal immune cells from nasal biopsies cells from 30 all...

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Detalles Bibliográficos
Autores principales: Voskamp, Astrid L., Tak, Tamar, Gerdes, Maarten L., Menafra, Roberta, Duijster, Ellen, Jochems, Simon P., Kielbasa, Szymon M., Kormelink, Tom Groot, Stam, Koen A., van Hengel, Oscar R.J., de Jong, Nicolette W., Hendriks, Rudi W., Kloet, Susan L., Yazdanbakhsh, Maria, de Jong, Esther C., Gerth van Wijk, Roy, Smits, Hermelijn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333709/
https://www.ncbi.nlm.nih.gov/pubmed/37428185
http://dx.doi.org/10.1084/jem.20221111