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Ceftolozane/tazobactam heteroresistance in cystic fibrosis-related Pseudomonas aeruginosa infections

OBJECTIVES: Cystic fibrosis (CF) patients are often colonized with Pseudomonas aeruginosa. During treatment, P. aeruginosa can develop subpopulations exhibiting variable in vitro antimicrobial (ABX) susceptibility patterns. Heteroresistance (HR) may underlie reported discrepancies between in vitro s...

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Detalles Bibliográficos
Autores principales: Monogue, Marguerite L, Sanders, James M, Pybus, Christine A, Kim, Jiwoong, Zhan, Xiaowei, Clark, Andrew E, Greenberg, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333726/
https://www.ncbi.nlm.nih.gov/pubmed/37441352
http://dx.doi.org/10.1093/jacamr/dlad083