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Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma

BACKGROUND: Salivary adenoid cystic carcinoma (SACC) is a unique malignant tumor of the salivary gland with poor prognosis, which is not effective with chemotherapy and targeted drugs. Therefore, it is important to explore the molecular mechanism underlying SACC invasion and metastasis to develop no...

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Detalles Bibliográficos
Autores principales: Jiang, Liehao, Liu, Yunye, Pan, Yan, Tan, Zhuo, Wang, Jiafeng, Zheng, Guowan, Qian, Chenhong, Xu, Shiying, Zhu, Xin, Ma, Wenli, Guerrini, Susanna, Infante-Cossio, Pedro, Wu, Jiajun, Ge, Minghua, Cai, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333761/
https://www.ncbi.nlm.nih.gov/pubmed/37441023
http://dx.doi.org/10.21037/gs-23-127