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Transcription factor expression is the main determinant of variability in gene co‐activity

Many genes are co‐expressed and form genomic domains of coordinated gene activity. However, the regulatory determinants of domain co‐activity remain unclear. Here, we leverage human individual variation in gene expression to characterize the co‐regulatory processes underlying domain co‐activity and...

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Detalles Bibliográficos
Autores principales: van Duin, Lucas, Krautz, Robert, Rennie, Sarah, Andersson, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333863/
https://www.ncbi.nlm.nih.gov/pubmed/37158788
http://dx.doi.org/10.15252/msb.202211392