An Optogenetics-based Approach to Regulate Colonic Contractions by Modulating the Activity of the Interstitial Cells of Cajal in Mice

BACKGROUND/AIMS: The interstitial cells of Cajal (ICC) are pacemaker cells in the gastrointestinal (GI) tract. We examined whether the activity of ICC could be stimulated to control colonic contractions. An optogenetics-based mouse model in which the light-sensitive protein channelrhodopsin-2 (ChR2)...

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Detalles Bibliográficos
Autores principales: Zhao, Song, Tong, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Neurogastroenterology and Motility 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334192/
https://www.ncbi.nlm.nih.gov/pubmed/37417266
http://dx.doi.org/10.5056/jnm22181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334192/
https://www.ncbi.nlm.nih.gov/pubmed/37417266
http://dx.doi.org/10.5056/jnm22181

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