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Topical delivery of ebselen encapsulated in biopolymeric nanocapsules: drug repurposing enhanced antifungal activity

AIM: Ebselen (Eb) is an example of a repurposed drug with poor aqueous solubility which requires sophisticated delivery system such as nanoencapsulation in nanocapsules for topical application. MATERIALS & METHODS: Eb-nanocapsules were examined for morphology, activity against Candida spp., cyto...

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Detalles Bibliográficos
Autores principales: Jaromin, Anna, Zarnowski, Robert, Piętka-Ottlik, Magdalena, Andes, David R, Gubernator, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334256/
https://www.ncbi.nlm.nih.gov/pubmed/29873597
http://dx.doi.org/10.2217/nnm-2017-0337